MyBioSource.com's XDH Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The XDH Antibody was generated using Xanthine Dehydrogenase, and XDH as the antigen and it reacts with Human, and Rat.
Description
Function: Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Subunit Structure: Homodimer. Interacts with BTN1A1 (By similarity).
Post-translational Modifications: Subject to partial proteolysis; this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O). Contains sulfhydryl groups that are easily oxidized (in vitro); this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O).
Similarity: Belongs to the xanthine dehydrogenase family